Cargando…
COBRA methods and metabolic drug targets in cancer
The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis) framework for metabolic networks, to perform th...
Autores principales: | Apaolaza, Iñigo, José-Eneriz, Edurne San, Agirre, Xabier, Prósper, Felipe, Planes, Francisco J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791858/ https://www.ncbi.nlm.nih.gov/pubmed/29404389 http://dx.doi.org/10.1080/23723556.2017.1389672 |
Ejemplares similares
-
A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism
por: Apaolaza, Iñigo, et al.
Publicado: (2022) -
An in-silico approach to predict and exploit synthetic lethality in cancer metabolism
por: Apaolaza, Iñigo, et al.
Publicado: (2017) -
In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer
por: Pey, Jon, et al.
Publicado: (2017) -
BOSO: A novel feature selection algorithm for linear regression with high-dimensional data
por: Valcárcel, Luis V., et al.
Publicado: (2022) -
HDAC Inhibitors in Acute Myeloid Leukemia
por: San José-Enériz, Edurne, et al.
Publicado: (2019)