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Controlling hepatitis C in Rwanda: a framework for a national response

With the introduction of direct-acting antiviral drugs, treatment of hepatitis C is both highly effective and tolerable. Access to treatment for patients, however, remains limited in low- and middle-income countries due to the lack of supportive health infrastructure and the high cost of treatment....

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Autores principales: Mbituyumuremyi, Aimable, Van Nuil, Jennifer Ilo, Umuhire, Jeanne, Mugabo, Jules, Mwumvaneza, Mutagoma, Makuza, Jean Damascene, Umutesi, Justine, Nsanzimana, Sabin, Gupta, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Health Organization 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791867/
https://www.ncbi.nlm.nih.gov/pubmed/29403100
http://dx.doi.org/10.2471/BLT.16.183772
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author Mbituyumuremyi, Aimable
Van Nuil, Jennifer Ilo
Umuhire, Jeanne
Mugabo, Jules
Mwumvaneza, Mutagoma
Makuza, Jean Damascene
Umutesi, Justine
Nsanzimana, Sabin
Gupta, Neil
author_facet Mbituyumuremyi, Aimable
Van Nuil, Jennifer Ilo
Umuhire, Jeanne
Mugabo, Jules
Mwumvaneza, Mutagoma
Makuza, Jean Damascene
Umutesi, Justine
Nsanzimana, Sabin
Gupta, Neil
author_sort Mbituyumuremyi, Aimable
collection PubMed
description With the introduction of direct-acting antiviral drugs, treatment of hepatitis C is both highly effective and tolerable. Access to treatment for patients, however, remains limited in low- and middle-income countries due to the lack of supportive health infrastructure and the high cost of treatment. Poorer countries are being encouraged by international bodies to organize public health responses that would facilitate the roll-out of care and treatment on a national scale. Yet few countries have documented formal plans and policies. Here, we outline the approach taken in Rwanda to a public health framework for hepatitis C control and care within the World Health Organization hepatitis health sector strategy. This includes the development and implementation of policies and programmes, prevention efforts, screening capacity, treatment services and strategic information systems. We highlight key successes by the national programme for the control and management of hepatitis C: establishment of national governance and planning; development of diagnostic capacity; approval and introduction of direct-acting antiviral treatments; training of key personnel; generation of political will and leadership; and fostering of key strategic partnerships. Existing challenges and next steps for the programme include developing a detailed monitoring and evaluation framework and tools for monitoring of viral hepatitis. The government needs to further decentralize care and integrate hepatitis C management into routine clinical services to provide better access to diagnosis and treatment for patients. Introducing rapid diagnostic tests to public health-care facilities would help to increase case-finding. Increased public and private financing is essential to support care and treatment services.
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spelling pubmed-57918672018-02-05 Controlling hepatitis C in Rwanda: a framework for a national response Mbituyumuremyi, Aimable Van Nuil, Jennifer Ilo Umuhire, Jeanne Mugabo, Jules Mwumvaneza, Mutagoma Makuza, Jean Damascene Umutesi, Justine Nsanzimana, Sabin Gupta, Neil Bull World Health Organ Policy & Practice With the introduction of direct-acting antiviral drugs, treatment of hepatitis C is both highly effective and tolerable. Access to treatment for patients, however, remains limited in low- and middle-income countries due to the lack of supportive health infrastructure and the high cost of treatment. Poorer countries are being encouraged by international bodies to organize public health responses that would facilitate the roll-out of care and treatment on a national scale. Yet few countries have documented formal plans and policies. Here, we outline the approach taken in Rwanda to a public health framework for hepatitis C control and care within the World Health Organization hepatitis health sector strategy. This includes the development and implementation of policies and programmes, prevention efforts, screening capacity, treatment services and strategic information systems. We highlight key successes by the national programme for the control and management of hepatitis C: establishment of national governance and planning; development of diagnostic capacity; approval and introduction of direct-acting antiviral treatments; training of key personnel; generation of political will and leadership; and fostering of key strategic partnerships. Existing challenges and next steps for the programme include developing a detailed monitoring and evaluation framework and tools for monitoring of viral hepatitis. The government needs to further decentralize care and integrate hepatitis C management into routine clinical services to provide better access to diagnosis and treatment for patients. Introducing rapid diagnostic tests to public health-care facilities would help to increase case-finding. Increased public and private financing is essential to support care and treatment services. World Health Organization 2018-01-01 2017-11-27 /pmc/articles/PMC5791867/ /pubmed/29403100 http://dx.doi.org/10.2471/BLT.16.183772 Text en (c) 2018 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Policy & Practice
Mbituyumuremyi, Aimable
Van Nuil, Jennifer Ilo
Umuhire, Jeanne
Mugabo, Jules
Mwumvaneza, Mutagoma
Makuza, Jean Damascene
Umutesi, Justine
Nsanzimana, Sabin
Gupta, Neil
Controlling hepatitis C in Rwanda: a framework for a national response
title Controlling hepatitis C in Rwanda: a framework for a national response
title_full Controlling hepatitis C in Rwanda: a framework for a national response
title_fullStr Controlling hepatitis C in Rwanda: a framework for a national response
title_full_unstemmed Controlling hepatitis C in Rwanda: a framework for a national response
title_short Controlling hepatitis C in Rwanda: a framework for a national response
title_sort controlling hepatitis c in rwanda: a framework for a national response
topic Policy & Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791867/
https://www.ncbi.nlm.nih.gov/pubmed/29403100
http://dx.doi.org/10.2471/BLT.16.183772
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