MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption

Histone variants are structural components of eukaryotic chromatin that can replace replication-coupled histones in the nucleosome. The histone variant macroH2A.1.1 contains a macrodomain able to bind NAD(+) derived metabolites. Here, we report that macroH2A.1.1 is rapidly induced during myogenic di...

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Detalles Bibliográficos
Autores principales: Posavec Marjanović, Melanija, Hurtado-Bagès, Sarah, Lassi, Maximilian, Valero, Vanesa, Malinverni, Roberto, Delage, Hélène, Navarro, Miriam, Corujo, David, Guberovic, Iva, Douet, Julien, Gama-Perez, Pau, Garcia-Roves, Pablo M., Ahel, Ivan, Ladurner, Andreas G., Yanes, Oscar, Bouvet, Philippe, Suelves, Mònica, Teperino, Raffaele, Pospisilik, J. Andrew, Buschbeck, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791885/
https://www.ncbi.nlm.nih.gov/pubmed/28991266
http://dx.doi.org/10.1038/nsmb.3481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791885/
https://www.ncbi.nlm.nih.gov/pubmed/28991266
http://dx.doi.org/10.1038/nsmb.3481

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