Cargando…

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption

Histone variants are structural components of eukaryotic chromatin that can replace replication-coupled histones in the nucleosome. The histone variant macroH2A.1.1 contains a macrodomain able to bind NAD(+) derived metabolites. Here, we report that macroH2A.1.1 is rapidly induced during myogenic di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Posavec Marjanović, Melanija, Hurtado-Bagès, Sarah, Lassi, Maximilian, Valero, Vanesa, Malinverni, Roberto, Delage, Hélène, Navarro, Miriam, Corujo, David, Guberovic, Iva, Douet, Julien, Gama-Perez, Pau, Garcia-Roves, Pablo M., Ahel, Ivan, Ladurner, Andreas G., Yanes, Oscar, Bouvet, Philippe, Suelves, Mònica, Teperino, Raffaele, Pospisilik, J. Andrew, Buschbeck, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791885/ https://www.ncbi.nlm.nih.gov/pubmed/28991266 http://dx.doi.org/10.1038/nsmb.3481

Ejemplares similares

The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner
por: Hurtado-Bagès, Sarah, et al.
Publicado: (2020)

The MacroH2A1.1 – PARP1 Axis at the Intersection Between Stress Response and Metabolism
por: Hurtado-Bagès, Sarah, et al.
Publicado: (2018)

macroH2A1 histone variant represses rDNA transcription
por: Cong, Rong, et al.
Publicado: (2014)

Histone variant macroH2A1 deletion in mice causes female-specific steatosis
por: Boulard, Mathieu, et al.
Publicado: (2010)

The taming of PARP1 and its impact on NAD(+) metabolism
por: Hurtado-Bagès, Sarah, et al.
Publicado: (2020)

The Role of MacroH2A Histone Variants in Cancer
por: Hsu, Chen-Jen, et al.
Publicado: (2021)

Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype
por: Vieira-Silva, Tânia Soraia, et al.
Publicado: (2019)

Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions
por: Kumbhar, Ramhari, et al.
Publicado: (2021)

Phosphorylation within Intrinsic Disordered Region Discriminates Histone Variant macroH2A1 Splicing Isoforms—macroH2A1.1 and macroH2A1.2
por: Giallongo, Sebastiano, et al.
Publicado: (2021)

Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
por: Singh, Gurdeep, et al.
Publicado: (2022)

MacroH2A1 Immunoexpression in Breast Cancer
por: Broggi, Giuseppe, et al.
Publicado: (2020)

X Chromosome Inactivation and Differentiation Occur Readily in ES Cells Doubly-Deficient for MacroH2A1 and MacroH2A2
por: Tanasijevic, Borko, et al.
Publicado: (2011)

Author Correction: Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
por: Singh, Gurdeep, et al.
Publicado: (2022)

Histone variant macroH2A confers resistance to nuclear reprogramming
por: Pasque, Vincent, et al.
Publicado: (2011)

LSH mediates gene repression through macroH2A deposition
por: Ni, Kai, et al.
Publicado: (2020)

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma
por: Nikolic, Ana, et al.
Publicado: (2023)

regioneReloaded: evaluating the association of multiple genomic region sets
por: Malinverni, Roberto, et al.
Publicado: (2023)

The Histone Variant MacroH2A1 Impacts Circadian Gene Expression and Cell Phenotype in an In Vitro Model of Hepatocellular Carcinoma
por: Carbone, Annalucia, et al.
Publicado: (2021)

MacroH2A1 knockdown effects on the Peg3 imprinted domain
por: Choo, Jung Ha, et al.
Publicado: (2007)

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays
por: Muthurajan, Uma M., et al.
Publicado: (2011)

Transcription-associated histone pruning demarcates macroH2A chromatin domains
por: Sun, Zhen, et al.
Publicado: (2018)

Zebrafish macroH2A variants have distinct embryo localization and function
por: Gonzalez-Munoz, E., et al.
Publicado: (2019)

Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains
por: Sato, Hanae, et al.
Publicado: (2019)

Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome
por: Bereshchenko, Oxana, et al.
Publicado: (2019)

Cell cycle–dependent localization of macroH2A in chromatin of the inactive X chromosome
por: Chadwick, Brian P., et al.
Publicado: (2002)

The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome
por: Chakravarthy, Srinivas, et al.
Publicado: (2012)

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
por: Kapoor, Avnish, et al.
Publicado: (2010)

The Histone H2A Variant MacroH2A1 Does Not Localize to the Centrosome
por: Friedman, Nathalie, et al.
Publicado: (2011)

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma
por: Rappa, Francesca, et al.
Publicado: (2013)

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency
por: Gaspar-Maia, Alexandre, et al.
Publicado: (2013)

Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis
por: Pazienza, Valerio, et al.
Publicado: (2016)

Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm
por: Hu, Wan-Hsiang, et al.
Publicado: (2016)

The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment
por: Cedeno, Ryan James, et al.
Publicado: (2017)

Correction: Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma
por: Rappa, Francesca, et al.
Publicado: (2013)

MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells
por: Fu, Yuhua, et al.
Publicado: (2015)

The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening.
por: Kim, Jeongkyu, et al.
Publicado: (2019)

Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells
por: Giallongo, Sebastiano, et al.
Publicado: (2020)

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming
por: Mohammed Ismail, Wazim, et al.
Publicado: (2023)

Human macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast
por: Haase, Max A. B., et al.
Publicado: (2023)

Deficiency of histone variant macroH2A1.1 is associated with sexually dimorphic obesity in mice
por: Chiodi, Valentina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_833bov2bl4tsq5j202jj42f4vk