Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders

Antiviral drugs and alcohol abuse-induced organelle stresses have been linked to many disorders and the underlying molecular mechanisms are under intense investigations. This brief review communicates emerging evidence and research trends on how certain antivirals and alcohol affect ER-Golgi traffic...

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Detalles Bibliográficos
Autor principal: Ji, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791917/
https://www.ncbi.nlm.nih.gov/pubmed/29399658
http://dx.doi.org/10.21767/2471-853X.100054
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author Ji, Cheng
author_facet Ji, Cheng
author_sort Ji, Cheng
collection PubMed
description Antiviral drugs and alcohol abuse-induced organelle stresses have been linked to many disorders and the underlying molecular mechanisms are under intense investigations. This brief review communicates emerging evidence and research trends on how certain antivirals and alcohol affect ER-Golgi trafficking, which potentially impacts the function and integrity of the Golgi apparatus contributing to endoplasmic reticulum stress and cellular injury.
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spelling pubmed-57919172018-01-31 Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders Ji, Cheng J Drug Abuse Article Antiviral drugs and alcohol abuse-induced organelle stresses have been linked to many disorders and the underlying molecular mechanisms are under intense investigations. This brief review communicates emerging evidence and research trends on how certain antivirals and alcohol affect ER-Golgi trafficking, which potentially impacts the function and integrity of the Golgi apparatus contributing to endoplasmic reticulum stress and cellular injury. 2017-09-26 2017 /pmc/articles/PMC5791917/ /pubmed/29399658 http://dx.doi.org/10.21767/2471-853X.100054 Text en http://creativecommons.org/licenses/by/3.0/ Under License of Creative Commons Attribution 3.0 License
spellingShingle Article
Ji, Cheng
Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title_full Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title_fullStr Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title_full_unstemmed Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title_short Dissecting the Role of Disturbed ER-Golgi Trafficking in Antivirals and Alcohol Abuse-Induced Pathogenesis of Liver Disorders
title_sort dissecting the role of disturbed er-golgi trafficking in antivirals and alcohol abuse-induced pathogenesis of liver disorders
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791917/
https://www.ncbi.nlm.nih.gov/pubmed/29399658
http://dx.doi.org/10.21767/2471-853X.100054
work_keys_str_mv AT jicheng dissectingtheroleofdisturbedergolgitraffickinginantiviralsandalcoholabuseinducedpathogenesisofliverdisorders

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