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Combination COX-2 inhibitor and metformin attenuate rate of joint replacement in osteoarthritis with diabetes: A nationwide, retrospective, matched-cohort study in Taiwan

BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis associated with an increased prevalence of type 2 diabetes mellitus (T2DM), however their impact on decreasing joint replacement surgery has yet to be elucidated. This study aimed to investigate if the combination of COX-2 inhibito...

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Detalles Bibliográficos
Autores principales:	Lu, Chieh-Hua, Chung, Chi-Hsiang, Lee, Chien-Hsing, Hsieh, Chang-Hsun, Hung, Yi-Jen, Lin, Fu-Huang, Tsao, Chang-Huei, Hsieh, Po-Shiuan, Chien, Wu-Chien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791980/ https://www.ncbi.nlm.nih.gov/pubmed/29385156 http://dx.doi.org/10.1371/journal.pone.0191242

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