Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication

Transcription and replication of the influenza A virus (IAV) genome occur in the nucleus of infected cells and are carried out by the viral ribonucleoprotein complex (vRNP). As a major component of the vRNP complex, the viral nucleoprotein (NP) mediates the nuclear import of the vRNP complex via its...

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Detalles Bibliográficos
Autores principales: Luo, Weiyu, Zhang, Jie, Liang, Libin, Wang, Guangwen, Li, Qibing, Zhu, Pengyang, Zhou, Yuan, Li, Junping, Zhao, Yuhui, Sun, Nan, Huang, Shanyu, Zhou, Chenchen, Chang, Yu, Cui, Pengfei, Chen, Pucheng, Jiang, Yongping, Deng, Guohua, Bu, Zhigao, Li, Chengjun, Jiang, Li, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792031/
https://www.ncbi.nlm.nih.gov/pubmed/29352288
http://dx.doi.org/10.1371/journal.ppat.1006851

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