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A role for domain I of the hepatitis C virus NS5A protein in virus assembly

The NS5A protein of hepatitis C virus (HCV) plays roles in both virus genome replication and assembly. NS5A comprises three domains, of these domain I is believed to be involved exclusively in genome replication. In contrast, domains II and III are required for the production of infectious virus par...

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Detalles Bibliográficos
Autores principales: Yin, Chunhong, Goonawardane, Niluka, Stewart, Hazel, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792032/
https://www.ncbi.nlm.nih.gov/pubmed/29352312
http://dx.doi.org/10.1371/journal.ppat.1006834