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Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia

Chronic lymphocytic leukemia is a disease with up-regulated expression of the transmembrane tyrosine-protein kinase ROR1, a member of the Wnt/planar cell polarity pathway. In this study, we identified COBLL1 as a novel interaction partner of ROR1. COBLL1 shows clear bimodal expression with high leve...

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Detalles Bibliográficos
Autores principales: Plešingerová, Hana, Janovská, Pavlína, Mishra, Archana, Smyčková, Lucie, Poppová, Lucie, Libra, Antonín, Plevová, Karla, Ovesná, Petra, Radová, Lenka, Doubek, Michael, Pavlová, Šárka, Pospíšilová, Šárka, Bryja, Vítězslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792276/
https://www.ncbi.nlm.nih.gov/pubmed/29122990
http://dx.doi.org/10.3324/haematol.2017.178699