Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound

Rift Valley fever virus (RVFV) is a mosquito-borne hemorrhagic fever virus affecting both humans and animals with severe morbidity and mortality and is classified as a potential bioterror agent due to the possible aerosol transmission. At present there is no human vaccine or antiviral therapy availa...

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Detalles Bibliográficos
Autores principales: Islam, Md. Koushikul, Strand, Mårten, Saleeb, Michael, Svensson, Richard, Baranczewski, Pawel, Artursson, Per, Wadell, Göran, Ahlm, Clas, Elofsson, Mikael, Evander, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792431/
https://www.ncbi.nlm.nih.gov/pubmed/29386590
http://dx.doi.org/10.1038/s41598-018-20362-9

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