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TT(N)mGCCTC inhibits archaeal family B DNA polymerases

The proofreading activity of the archaeal family B DNA polymerases enables PCR with high fidelity. However, thermostable proofreading DNA polymerases occasionally failed to amplify target fragment that could be amplified by Taq DNA polymerase. We have previously showed that G-rich sequences, which f...

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Detalles Bibliográficos
Autores principales: Sun, Shuhui, Guo, Wei, Yang, Jin-Shu, Qiu, Mengsheng, Zhu, Xiao-Jing, Dai, Zhong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792436/
https://www.ncbi.nlm.nih.gov/pubmed/29386523
http://dx.doi.org/10.1038/s41598-018-20127-4