Nucleotide resolution mapping of influenza A virus nucleoprotein-RNA interactions reveals RNA features required for replication

Influenza A virus nucleoprotein (NP) association with viral RNA (vRNA) is essential for packaging, but the pattern of NP binding to vRNA is unclear. Here we applied photoactivatable ribonucleoside enhanced cross-linking and immunoprecipitation (PAR-CLIP) to assess the native-state of NP–vRNA interac...

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Detalles Bibliográficos
Autores principales: Williams, Graham D., Townsend, Dana, Wylie, Kristine M., Kim, Preston J., Amarasinghe, Gaya K., Kutluay, Sebla B., Boon, Adrianus C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792457/
https://www.ncbi.nlm.nih.gov/pubmed/29386621
http://dx.doi.org/10.1038/s41467-018-02886-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792457/
https://www.ncbi.nlm.nih.gov/pubmed/29386621
http://dx.doi.org/10.1038/s41467-018-02886-w

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