Recombinant Mtb9.8 of Mycobacterium bovis stimulates TNF-α and IL-1β secretion by RAW264.7 macrophages through activation of NF-κB pathway via TLR2

The Mtb9.8 antigenic protein of Mycobacterium bovis/Mycobacterium tuberculosis has been identified as a target of the T-cell response. However, the interaction of Mtb9.8 with Toll-like receptors (TLRs) and the relevant signaling pathways have not been fully clarified. In this study, recombinant Mtb9...

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Detalles Bibliográficos
Autores principales: Liu, Shuqing, Jia, Hong, Hou, Shaohua, Xin, Ting, Guo, Xiaoyu, Zhang, Gaimei, Gao, Xintao, Li, Ming, Zhu, Wuyang, Zhu, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792469/
https://www.ncbi.nlm.nih.gov/pubmed/29386556
http://dx.doi.org/10.1038/s41598-018-20433-x

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