Blockade of ACK1/TNK2 To Squelch the Survival of Prostate Cancer Stem-like Cells

Prostate cancer stem-like cells (PCSCs) are not only enriched in the CD44(+)PSA(−/lo) subpopulation but also employ androgen-independent signaling mechanisms for survival. CD44(+) PCSCs defy androgen deprivation, resist chemo- and radiotherapy and are highly tumorigenic. Human prostate tissue microa...

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Detalles Bibliográficos
Autores principales: Mahajan, Nupam P., Coppola, Domenico, Kim, Jongphil, Lawrence, Harshani R., Lawrence, Nicholas J., Mahajan, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792546/
https://www.ncbi.nlm.nih.gov/pubmed/29386546
http://dx.doi.org/10.1038/s41598-018-20172-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792546/
https://www.ncbi.nlm.nih.gov/pubmed/29386546
http://dx.doi.org/10.1038/s41598-018-20172-z

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