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Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice
There is, at present, no curative treatment for genetic hearing loss. We have previously reported that transuterine gene transfer of wild type CONNEXIN30 (CX30) genes into otocysts in CX30-deleted mice could restore hearing. Cell transplantation therapy might be another therapeutic option, although...
Autores principales: | Takeda, Hiroki, Hosoya, Makoto, Fujioka, Masato, Saegusa, Chika, Saeki, Tsubasa, Miwa, Toru, Okano, Hideyuki, Minoda, Ryosei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792596/ https://www.ncbi.nlm.nih.gov/pubmed/29386634 http://dx.doi.org/10.1038/s41598-018-20277-5 |
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