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Front Cover: Rhodol Derivatives as Selective Fluorescent Probes for the Detection of Hg(II) Ions and the Bioimaging of Hypochlorous Acid (ChemistryOpen 2/2018)

The Front Cover shows a novel rhodol‐based fluorescence probe from the structural combination of rhodamine and fluorescein motifs. Through the modification of the functional group on the spiro‐ring, high selectivity and sensitivity towards mercury(II) and hypochlorite ions are achieved, showing a si...

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Detalles Bibliográficos
Autores principales: Li, Ling, Wang, Shu, Lan, Hongxia, Gong, Guiyi, Zhu, Yifan, Tse, Yu Chung, Wong, Keith Man‐Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792732/
http://dx.doi.org/10.1002/open.201800009
Descripción
Sumario:The Front Cover shows a novel rhodol‐based fluorescence probe from the structural combination of rhodamine and fluorescein motifs. Through the modification of the functional group on the spiro‐ring, high selectivity and sensitivity towards mercury(II) and hypochlorite ions are achieved, showing a significant color change and fluorescence enhancement. Confocal microscopy images of HeLa cells incubated with the probe show enhanced fluorescence intensity with HClO, thus demonstrating the potential of the probe in further applications for in vivo HOCl detection. More information can be found in the Full Paper by L. Li et al. on page 136 in Issue 2, 2018 (DOI: 10.1002/open.201700154).[Image: see text]