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Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71‐year‐old male patient with high‐grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cy...

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Autores principales: Li, Xuanguang, Guo, Zhibin, Liu, Jinghao, Wei, Sen, Ren, Dian, Chen, Gang, Xu, Song, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792747/
https://www.ncbi.nlm.nih.gov/pubmed/29388384
http://dx.doi.org/10.1111/1759-7714.12565
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author Li, Xuanguang
Guo, Zhibin
Liu, Jinghao
Wei, Sen
Ren, Dian
Chen, Gang
Xu, Song
Chen, Jun
author_facet Li, Xuanguang
Guo, Zhibin
Liu, Jinghao
Wei, Sen
Ren, Dian
Chen, Gang
Xu, Song
Chen, Jun
author_sort Li, Xuanguang
collection PubMed
description Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71‐year‐old male patient with high‐grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cycles of adjuvant chemotherapy with paclitaxel and carboplatin were administered. There were no signs of relapse during 10 months of follow‐up. Furthermore, we reviewed the literature and summarized the surgical approaches, prognostic factors, and underlying genetic mechanisms of PMEC, which will benefit clinical treatment.
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spelling pubmed-57927472018-02-12 Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review Li, Xuanguang Guo, Zhibin Liu, Jinghao Wei, Sen Ren, Dian Chen, Gang Xu, Song Chen, Jun Thorac Cancer Case Reports Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71‐year‐old male patient with high‐grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cycles of adjuvant chemotherapy with paclitaxel and carboplatin were administered. There were no signs of relapse during 10 months of follow‐up. Furthermore, we reviewed the literature and summarized the surgical approaches, prognostic factors, and underlying genetic mechanisms of PMEC, which will benefit clinical treatment. John Wiley & Sons Australia, Ltd 2017-11-28 2018-02 /pmc/articles/PMC5792747/ /pubmed/29388384 http://dx.doi.org/10.1111/1759-7714.12565 Text en © 2017 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Li, Xuanguang
Guo, Zhibin
Liu, Jinghao
Wei, Sen
Ren, Dian
Chen, Gang
Xu, Song
Chen, Jun
Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title_full Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title_fullStr Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title_full_unstemmed Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title_short Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review
title_sort clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: case report and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792747/
https://www.ncbi.nlm.nih.gov/pubmed/29388384
http://dx.doi.org/10.1111/1759-7714.12565
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