Cargando…

Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase

Pulmonary fibrosis (PF) is one of the most prevalent causes of death following paraquat (PQ) poisoning. As demonstrated in previous studies by the present authors, epithelial-to-mesenchymal transition (EMT) is associated with PQ-induced PF. In addition, hypoxia-inducible factor-1α (HIF-1α) and lysyl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Jian, Qian, Yongbing, Jin, Wei, Tian, Rui, Zhu, Yong, Wang, Jinfeng, Meng, Xiaoxiao, Wang, Ruilan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792814/ https://www.ncbi.nlm.nih.gov/pubmed/29467842 http://dx.doi.org/10.3892/etm.2017.5677

Ejemplares similares

Endoplasmic reticulum stress promotes epithelial-mesenchymal transition via the PERK signaling pathway in paraquat-induced pulmonary fibrosis
por: Meng, Xiaoxiao, et al.
Publicado: (2021)

Lysyl Oxidase at the Crossroads of Mesenchymal Stem Cells and Epithelial-Mesenchymal Transition
por: Thomas, Clémence, et al.
Publicado: (2013)

HIF‐1α regulates EMT via the Snail and β‐catenin pathways in paraquat poisoning‐induced early pulmonary fibrosis
por: Zhu, Yong, et al.
Publicado: (2016)

Lysyl oxidase induces epithelial‐mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma
por: Umezaki, Naoki, et al.
Publicado: (2019)

Lysyl oxidase and hypoxia-inducible factor 1α: biomarkers of gastric cancer
por: Han, Ya-Lin, et al.
Publicado: (2019)

Neonatal exposure to hypoxia induces early arterial stiffening via activation of lysyl oxidases
por: Steppan, Jochen, et al.
Publicado: (2023)

Targeting lysyl oxidase reduces peritoneal fibrosis
por: Harlow, Christopher R., et al.
Publicado: (2017)

Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
por: Perryman, Lara, et al.
Publicado: (2022)

Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis
por: Guo, Liang, et al.
Publicado: (2015)

A positive feedback loop promotes HIF‐1α stability through miR‐210‐mediated suppression of RUNX3 in paraquat‐induced EMT
por: Zhu, Yong, et al.
Publicado: (2017)

Paraquat poisoning induced pulmonary epithelial mesenchymal transition through Notch1 pathway
por: Li, Tiegang, et al.
Publicado: (2017)

Involvement of epithelial-to-mesenchymal transition and associated transforming growth factor-β/Smad signaling in paraquat-induced pulmonary fibrosis
por: HAN, YING-YING, et al.
Publicado: (2015)

Lysyl oxidase family members in urological tumorigenesis and fibrosis
por: Li, Tao, et al.
Publicado: (2018)

The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins
por: Vallet, Sylvain D., et al.
Publicado: (2020)

Hypoxia-induced epithelial-mesenchymal transition and fibrosis for the development of breast capsular contracture
por: Kuo, Yao-Lung, et al.
Publicado: (2019)

Porous Se@SiO(2) nanospheres treated paraquat-induced acute lung injury by resisting oxidative stress
por: Zhu, Yong, et al.
Publicado: (2017)

Multifunctional Lysyl Oxidases
por: Trackman, Philip C.
Publicado: (2023)

Effect of Lysyl Oxidase G473A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis
por: Mukherjee, Sanjit, et al.
Publicado: (2021)

Lysyl Oxidase and the Tumor Microenvironment
por: Wang, Tong-Hong, et al.
Publicado: (2016)

Protective Effect of Anthocyanin on Paraquat-Induced Apoptosis and Epithelial-Mesenchymal Transition in Alveolar Type II Cells
por: Wang, Zhihua, et al.
Publicado: (2018)

Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition
por: de Jong, Olivier G., et al.
Publicado: (2018)

Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond
por: Tam, Shing Yau, et al.
Publicado: (2020)

Inhibition of lysyl oxidase‑like 2 ameliorates folic acid‑induced renal tubulointerstitial fibrosis
por: Choi, Sung-Eun, et al.
Publicado: (2022)

Lysyl oxidase‐like 2 inhibitor rescues D‐galactose‐induced skeletal muscle fibrosis
por: Wu, Yongxin, et al.
Publicado: (2022)

Origin and evolution of lysyl oxidases
por: Grau-Bové, Xavier, et al.
Publicado: (2015)

Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis
por: Sasaki, Masaru, et al.
Publicado: (2023)

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma
por: Zhang, Lin, et al.
Publicado: (2013)

Ionizing radiation induces tumor cell lysyl oxidase secretion
por: Shen, Colette J, et al.
Publicado: (2014)

Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse
por: Nguyen, Long T., et al.
Publicado: (2021)

Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
por: Tjin, Gavin, et al.
Publicado: (2017)

Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis
por: Aumiller, Verena, et al.
Publicado: (2017)

2027 The role of lysyl oxidase in systemic sclerosis-associated lung fibrosis
por: Nguyen, Xinh-Xinh, et al.
Publicado: (2018)

An in situ activity assay for lysyl oxidases
por: Wang, Huilei, et al.
Publicado: (2021)

Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism
por: Gao, Liang, et al.
Publicado: (2017)

Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
por: Liu, Yang, et al.
Publicado: (2012)

Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α
por: Yang, Yeon Ju, et al.
Publicado: (2015)

Inflammation‐induced macrophage lysyl oxidase in adipose stiffening and dysfunction in obesity
por: Huang, An, et al.
Publicado: (2021)

Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells
por: Yamada, Atsushi, et al.
Publicado: (2015)

Hypoxia promotes invasion and metastasis of breast cancer cells by increasing lysyl oxidase expression
por: Erler, JT, et al.
Publicado: (2005)

Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen-induced arthritis
por: Wang, Fan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0sdpliaflbpee3ajp9g5t7mudo