Cargando…

Cellular and Molecular Aspects of the β-N-Methylamino-l-alanine (BMAA) Mode of Action within the Neurodegenerative Pathway: Facts and Controversy

The implication of the cyanotoxin β-N-methylamino-l-alanine (BMAA) in long-lasting neurodegenerative disorders is still a matter of controversy. It has been alleged that chronic ingestion of BMAA through the food chain could be a causative agent of amyotrophic lateral sclerosis (ALS) and several rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Delcourt, Nicolas, Claudepierre, Thomas, Maignien, Thomas, Arnich, Nathalie, Mattei, César
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793093/ https://www.ncbi.nlm.nih.gov/pubmed/29271898 http://dx.doi.org/10.3390/toxins10010006

Ejemplares similares

Occurrence of β-N-methylamino-l-alanine (BMAA) and Isomers in Aquatic Environments and Aquatic Food Sources for Humans
por: Lance, Emilie, et al.
Publicado: (2018)

Correction: Occurrence of β-N-methylamino-l-alanine (BMAA) and Isomers in Aquatic Environments and Aquatic Food Sources for Humans. Toxins 2018, 10, 83
por: Lance, Emilie, et al.
Publicado: (2018)

Cyanobacterial Neurotoxin β-N-Methylamino-L-alanine (BMAA) in Shark Fins
por: Mondo, Kiyo, et al.
Publicado: (2012)

Production of β-methylamino-L-alanine (BMAA) and Its Isomers by Freshwater Diatoms
por: Violi, Jake P., et al.
Publicado: (2019)

Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake
por: Lage, Sandra, et al.
Publicado: (2015)

β-methylamino-L-alanine (BMAA) is not found in the brains of patients with confirmed Alzheimer’s disease
por: Meneely, Julie P., et al.
Publicado: (2016)

Transfer of the Neurotoxin β-N-methylamino-l-alanine (BMAA) in the Agro–Aqua Cycle
por: Kim, Sea-Yong, et al.
Publicado: (2020)

β-N-Methylamino-L-Alanine (BMAA) Modulates the Sympathetic Regulation and Homeostasis of Polyamines
por: Shkodrova, Milena, et al.
Publicado: (2023)

Environmental Neurotoxin β-N-Methylamino-L-alanine (BMAA) as a Widely Occurring Putative Pathogenic Factor in Neurodegenerative Diseases
por: Lopicic, Srdjan, et al.
Publicado: (2022)

β-N-Methylamino-l-alanine (BMAA) Toxicity Is Gender and Exposure-Age Dependent in Rats
por: Scott, Laura Louise, et al.
Publicado: (2017)

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets
por: Jiang, Liying, et al.
Publicado: (2014)

The cyanobacterial neurotoxin β-N-methylamino-l-alanine (BMAA) targets the olfactory bulb region
por: Pierozan, Paula, et al.
Publicado: (2020)

Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions
por: Zimmerman, David, et al.
Publicado: (2016)

New Typical Vector of Neurotoxin β-N-Methylamino-l-Alanine (BMAA) in the Marine Benthic Ecosystem
por: Li, Aifeng, et al.
Publicado: (2016)

β-N-methylamino-L-alanine (BMAA) suppresses cell cycle progression of non-neuronal cells
por: Okamoto, Saki, et al.
Publicado: (2018)

Non-Proteinogenic Amino Acid β-N-Methylamino-L-Alanine (BMAA): Bioactivity and Ecological Significance
por: Koksharova, Olga A., et al.
Publicado: (2022)

Maternal Transfer of the Cyanobacterial Neurotoxin β-N-Methylamino-L-Alanine (BMAA) via Milk to Suckling Offspring
por: Andersson, Marie, et al.
Publicado: (2013)

Gut microbiomes of cycad-feeding insects tolerant to β-methylamino-L-alanine (BMAA) are rich in siderophore biosynthesis
por: Gutiérrez-García, Karina, et al.
Publicado: (2023)

β-N-Methylamino-l-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
por: Engskog, Mikael K. R., et al.
Publicado: (2017)

Analysis of β-N-methylamino-L-alanine (BMAA) in spirulina-containing supplements by liquid chromatography-tandem mass spectrometry
por: McCarron, Pearse, et al.
Publicado: (2014)

Correction: Maternal Transfer of the Cyanobacterial Neurotoxin β-N-Methylamino-L-Alanine (BMAA) via Milk to Suckling Offspring
por: Andersson, Marie, et al.
Publicado: (2015)

ALS-linked SOD1 in glial cells enhances ß-N-Methylamino L-Alanine (BMAA)-induced toxicity in Drosophila
por: Islam, Rafique, et al.
Publicado: (2012)

Metabolic profiling of zebrafish (Danio rerio) embryos by NMR spectroscopy reveals multifaceted toxicity of β-methylamino-L-alanine (BMAA)
por: Roy, Upasana, et al.
Publicado: (2017)

Effects of the Toxic Non-Protein Amino Acid β-Methylamino-L-Alanine (BMAA) on Intracellular Amino Acid Levels in Neuroblastoma Cells
por: Violi, Jake P., et al.
Publicado: (2023)

Proteomic Insights into Starvation of Nitrogen-Replete Cells of Nostoc sp. PCC 7120 under β-N-Methylamino-L-Alanine (BMAA) Treatment
por: Koksharova, Olga A., et al.
Publicado: (2020)

Environmental neurotoxin interaction with proteins: Dose-dependent increase of free and protein-associated BMAA (β-N-methylamino-L-alanine) in neonatal rat brain
por: Karlsson, Oskar, et al.
Publicado: (2015)

Analysis of the neurotoxin β-N-methylamino-L-alanine (BMAA) and isomers in surface water by FMOC derivatization liquid chromatography high resolution mass spectrometry
por: Vo Duy, Sung, et al.
Publicado: (2019)

The Proposed Neurotoxin β-N-Methylamino-l-Alanine (BMAA) Is Taken up through Amino-Acid Transport Systems in the Cyanobacterium Anabaena PCC 7120
por: Wang, Zi-Qian, et al.
Publicado: (2020)

β-N-Methylamino-L-Alanine (BMAA) Causes Severe Stress in Nostoc sp. PCC 7120 Cells under Diazotrophic Conditions: A Proteomic Study
por: Koksharova, Olga A., et al.
Publicado: (2021)

Simultaneous Analysis of Cyanotoxins β-N-methylamino-L-alanine (BMAA) and Microcystins-RR, -LR, and -YR Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)
por: Pravadali-Cekic, Sercan, et al.
Publicado: (2023)

Gliotoxicity of the cyanotoxin, β-methyl-amino-(L)-alanine (BMAA)
por: Chiu, Alexander S., et al.
Publicado: (2013)

Quality Measures of Imaging Mass Spectrometry Aids in Revealing Long-term Striatal Protein Changes Induced by Neonatal Exposure to the Cyanobacterial Toxin β-N-methylamino-L-alanine (BMAA)
por: Karlsson, Oskar, et al.
Publicado: (2014)

Is Exposure to BMAA a Risk Factor for Neurodegenerative Diseases? A Response to a Critical Review of the BMAA Hypothesis
por: RA, Dunlop, et al.
Publicado: (2021)

Pinnatoxins’ Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health
por: Delcourt, Nicolas, et al.
Publicado: (2019)

The Emerging Science of BMAA: Do Cyanobacteria Contribute to Neurodegenerative Disease?
por: Holtcamp, Wendee
Publicado: (2012)

Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model
por: Al-Sammak, Maitham Ahmed, et al.
Publicado: (2015)

The Cyanobacteria Derived Toxin Beta-N-Methylamino-L-Alanine and Amyotrophic Lateral Sclerosis
por: Banack, Sandra Anne, et al.
Publicado: (2010)

The Changes in Cyanobacterial Concentration of β-Methylamino-L-Alanine during a Bloom Event
por: Peters, Siobhan J., et al.
Publicado: (2022)

β-N-Methylamino-L-alanine Induces Neurological Deficits and Shortened Life Span in Drosophila
por: Zhou, Xianchong, et al.
Publicado: (2010)

Human Scalp Hair as an Indicator of Exposure to the Environmental Toxin β-N-Methylamino-l-alanine
por: Downing, Simoné, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lapsg3oq7p14j6c43gq2ecb3up