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Signaling Pathways Driving Aberrant Splicing in Cancer Cells

Aberrant profiles of pre-mRNA splicing are frequently observed in cancer. At the molecular level, an altered profile results from a complex interplay between chromatin modifications, the transcriptional elongation rate of RNA polymerase, and effective binding of the spliceosome to the generated tran...

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Detalles Bibliográficos
Autores principales:	Gonçalves, Vânia, Pereira, Joana F. S., Jordan, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793162/ https://www.ncbi.nlm.nih.gov/pubmed/29286307 http://dx.doi.org/10.3390/genes9010009

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