Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells

In this review, we address aspects of Wnt, R-Spondin (RSPO) and Hippo signalling, in both healthy and transformed intestinal epithelium. In intestinal stem cells (ISCs), the Wnt pathway is essential for intestinal crypt formation and renewal, whereas RSPO-mediated signalling mainly affects ISC numbe...

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Detalles Bibliográficos
Autores principales: Kriz, Vitezslav, Korinek, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793173/
https://www.ncbi.nlm.nih.gov/pubmed/29316729
http://dx.doi.org/10.3390/genes9010020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793173/
https://www.ncbi.nlm.nih.gov/pubmed/29316729
http://dx.doi.org/10.3390/genes9010020

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