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Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells

The ability to produce recombinant proteins by utilizing different “cell factories” revolutionized the biotherapeutic and pharmaceutical industry. Chinese hamster ovary (CHO) cells are the dominant industrial producer, especially for antibodies. Human embryonic kidney cells (HEK), while not being as...

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Detalles Bibliográficos
Autores principales: Inwood, Sarah, Betenbaugh, Michael J., Shiloach, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793178/
https://www.ncbi.nlm.nih.gov/pubmed/29315258
http://dx.doi.org/10.3390/genes9010025