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Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells
The ability to produce recombinant proteins by utilizing different “cell factories” revolutionized the biotherapeutic and pharmaceutical industry. Chinese hamster ovary (CHO) cells are the dominant industrial producer, especially for antibodies. Human embryonic kidney cells (HEK), while not being as...
Autores principales: | Inwood, Sarah, Betenbaugh, Michael J., Shiloach, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793178/ https://www.ncbi.nlm.nih.gov/pubmed/29315258 http://dx.doi.org/10.3390/genes9010025 |
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