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A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability
BACKGROUND: Due to limited coding capacity of viral genome, enterovirus A71 (EV-A71) co-opts host nuclear proteins for its replication. Upon ER stress, the ER-localized 90 kDa activating transcription factor 6 (p90ATF6) is proteolytically cleaved to produce the transcriptionally active amino-termina...
Autores principales: | Jheng, Jia-Rong, Lau, Kean-Seng, Lan, Yueh-Wen, Horng, Jim-Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793394/ https://www.ncbi.nlm.nih.gov/pubmed/29386036 http://dx.doi.org/10.1186/s12929-018-0412-x |
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