A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability

BACKGROUND: Due to limited coding capacity of viral genome, enterovirus A71 (EV-A71) co-opts host nuclear proteins for its replication. Upon ER stress, the ER-localized 90 kDa activating transcription factor 6 (p90ATF6) is proteolytically cleaved to produce the transcriptionally active amino-termina...

Descripción completa

Detalles Bibliográficos
Autores principales: Jheng, Jia-Rong, Lau, Kean-Seng, Lan, Yueh-Wen, Horng, Jim-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793394/
https://www.ncbi.nlm.nih.gov/pubmed/29386036
http://dx.doi.org/10.1186/s12929-018-0412-x

Ejemplares similares

Ejemplares similares