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Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia

This work deals with the synthesis and characterization of novel Fe-containing sol-gel materials obtained by modifying the composition of a binary SiO(2)-CaO parent glass with the addition of Fe(2)O(3). The effect of different processing conditions (calcination in air vs. argon flowing) on the forma...

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Autores principales: Baino, Francesco, Fiume, Elisa, Miola, Marta, Leone, Federica, Onida, Barbara, Laviano, Francesco, Gerbaldo, Roberto, Verné, Enrica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793671/
https://www.ncbi.nlm.nih.gov/pubmed/29361763
http://dx.doi.org/10.3390/ma11010173
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author Baino, Francesco
Fiume, Elisa
Miola, Marta
Leone, Federica
Onida, Barbara
Laviano, Francesco
Gerbaldo, Roberto
Verné, Enrica
author_facet Baino, Francesco
Fiume, Elisa
Miola, Marta
Leone, Federica
Onida, Barbara
Laviano, Francesco
Gerbaldo, Roberto
Verné, Enrica
author_sort Baino, Francesco
collection PubMed
description This work deals with the synthesis and characterization of novel Fe-containing sol-gel materials obtained by modifying the composition of a binary SiO(2)-CaO parent glass with the addition of Fe(2)O(3). The effect of different processing conditions (calcination in air vs. argon flowing) on the formation of magnetic crystalline phases was investigated. The produced materials were analyzed from thermal (hot-stage microscopy, differential thermal analysis, and differential thermal calorimetry) and microstructural (X-ray diffraction) viewpoints to assess both the behavior upon heating and the development of crystalline phases. N(2) adsorption–desorption measurements allowed determining that these materials have high surface area (40–120 m(2)/g) and mesoporous texture with mesopore size in the range of 18 to 30 nm. It was assessed that the magnetic properties can actually be tailored by controlling the Fe content and the environmental conditions (oxidant vs. inert atmosphere) during calcination. The glasses and glass-ceramics developed in this work show promise for applications in bone tissue healing which require the use of biocompatible magnetic implants able to elicit therapeutic actions, such as hyperthermia for bone cancer treatment.
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spelling pubmed-57936712018-02-07 Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia Baino, Francesco Fiume, Elisa Miola, Marta Leone, Federica Onida, Barbara Laviano, Francesco Gerbaldo, Roberto Verné, Enrica Materials (Basel) Article This work deals with the synthesis and characterization of novel Fe-containing sol-gel materials obtained by modifying the composition of a binary SiO(2)-CaO parent glass with the addition of Fe(2)O(3). The effect of different processing conditions (calcination in air vs. argon flowing) on the formation of magnetic crystalline phases was investigated. The produced materials were analyzed from thermal (hot-stage microscopy, differential thermal analysis, and differential thermal calorimetry) and microstructural (X-ray diffraction) viewpoints to assess both the behavior upon heating and the development of crystalline phases. N(2) adsorption–desorption measurements allowed determining that these materials have high surface area (40–120 m(2)/g) and mesoporous texture with mesopore size in the range of 18 to 30 nm. It was assessed that the magnetic properties can actually be tailored by controlling the Fe content and the environmental conditions (oxidant vs. inert atmosphere) during calcination. The glasses and glass-ceramics developed in this work show promise for applications in bone tissue healing which require the use of biocompatible magnetic implants able to elicit therapeutic actions, such as hyperthermia for bone cancer treatment. MDPI 2018-01-22 /pmc/articles/PMC5793671/ /pubmed/29361763 http://dx.doi.org/10.3390/ma11010173 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Baino, Francesco
Fiume, Elisa
Miola, Marta
Leone, Federica
Onida, Barbara
Laviano, Francesco
Gerbaldo, Roberto
Verné, Enrica
Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title_full Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title_fullStr Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title_full_unstemmed Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title_short Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia
title_sort fe-doped sol-gel glasses and glass-ceramics for magnetic hyperthermia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793671/
https://www.ncbi.nlm.nih.gov/pubmed/29361763
http://dx.doi.org/10.3390/ma11010173
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