Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles in sperm of se...

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Detalles Bibliográficos
Autores principales: Qu, Jianghan, Hodges, Emily, Molaro, Antoine, Gagneux, Pascal, Dean, Matthew D., Hannon, Gregory J., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793779/
https://www.ncbi.nlm.nih.gov/pubmed/29259021
http://dx.doi.org/10.1101/gr.225896.117

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