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A Positron Emission Tomography Study of Norepinephrine Transporter Occupancy and Its Correlation with Symptom Response in Depressed Patients Treated with Quetiapine XR

BACKGROUND: Quetiapine is effective in treating depressive symptoms in major depressive disorder and bipolar disorder, but the mechanisms underlying its antidepressants effects are unknown. Norquetiapine, a metabolite of quetiapine, has high affinity for norepinephrine transporter, which might accou...

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Detalles Bibliográficos
Autores principales:	Yatham, Lakshmi N, Sossi, Vesna, Ding, Yu-Shin, Vafai, Nasim, Arumugham, Shyam Sundar, Dhanoa, Taj, Lam, Raymond W, Bond, David J, Puyat, Joseph H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Regular Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793822/ https://www.ncbi.nlm.nih.gov/pubmed/29016993 http://dx.doi.org/10.1093/ijnp/pyx066

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