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Resolving systematic errors in widely-used enhancer activity assays in human cells
The identification of transcriptional enhancers in the human genome is a prime goal in biology. Enhancers are typically predicted via chromatin marks, yet their function is primarily assessed with plasmid-based reporter assays. Here, we show that two previous observations relating to plasmid-transfe...
Autores principales: | Muerdter, Felix, Boryń, Łukasz M., Woodfin, Ashley R., Neumayr, Christoph, Rath, Martina, Zabidi, Muhammad A., Pagani, Michaela, Haberle, Vanja, Kazmar, Tomáš, Catarino, Rui R., Schernhuber, Katharina, Arnold, Cosmas D., Stark, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793997/ https://www.ncbi.nlm.nih.gov/pubmed/29256496 http://dx.doi.org/10.1038/nmeth.4534 |
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