Cargando…

Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen

BACKGROUND: Obesity is a well-known risk factor of breast cancer in post-menopausal women that also correlates with a diminished therapeutic response. The influence of adipocytes and their secretome, i.e. adipokines, on the efficacy of hormone therapy has yet to be elucidated. METHODS: We investigat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bougaret, Lauriane, Delort, Laetitia, Billard, Hermine, Le Huede, Camille, Boby, Céline, De la Foye, Anne, Rossary, Adrien, Mojallal, Ali, Damour, Odile, Auxenfans, Céline, Vasson, Marie Paule, Caldefie-Chezet, Florence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794086/ https://www.ncbi.nlm.nih.gov/pubmed/29389973 http://dx.doi.org/10.1371/journal.pone.0191571

Ejemplares similares

Reciprocal Interactions between Breast Tumor and Its Adipose Microenvironment Based on a 3D Adipose Equivalent Model
por: Delort, Laetitia, et al.
Publicado: (2013)

Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin
por: Delort, Laetitia, et al.
Publicado: (2019)

Breast Cancer and Obesity: In Vitro Interferences between Adipokines and Proangiogenic Features and/or Antitumor Therapies?
por: Dubois, Virginie, et al.
Publicado: (2013)

The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer
por: Delort, Laetitia, et al.
Publicado: (2021)

Aspalathus linearis (Rooibos) Targets Adipocytes and Obesity-Associated Inflammation
por: Nehme, Rawan, et al.
Publicado: (2023)

Spontaneous Physical Activity in Obese Condition Favours Antitumour Immunity Leading to Decreased Tumour Growth in a Syngeneic Mouse Model of Carcinogenesis
por: Le Guennec, Delphine, et al.
Publicado: (2021)

Modulation of inter-organ signalling in obese mice by spontaneous physical activity during mammary cancer development
por: Le Guennec, Delphine, et al.
Publicado: (2020)

3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages
por: Habanjar, Ola, et al.
Publicado: (2021)

The Impact of Obesity, Adipose Tissue, and Tumor Microenvironment on Macrophage Polarization and Metastasis
por: Habanjar, Ola, et al.
Publicado: (2022)

Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer
por: Nachat-Kappes, Rachida, et al.
Publicado: (2012)

Targeting Adiponectin in Breast Cancer
por: Nehme, Rawan, et al.
Publicado: (2022)

Crosstalk of Inflammatory Cytokines within the Breast Tumor Microenvironment
por: Habanjar, Ola, et al.
Publicado: (2023)

EO771, the first luminal B mammary cancer cell line from C57BL/6 mice
por: Le Naour, Augustin, et al.
Publicado: (2020)

Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen
por: Basu, Samar, et al.
Publicado: (2015)

EO771, is it a well‐characterized cell line for mouse mammary cancer model? Limit and uncertainty
por: Le Naour, Augustin, et al.
Publicado: (2020)

Evaluation of Three Devices for the Isolation of the Stromal Vascular Fraction from Adipose Tissue and for ASC Culture: A Comparative Study
por: Rodriguez, Jonathan, et al.
Publicado: (2017)

Chemical Profile, Antioxidant and Anti-Inflammatory Potency of Extracts of Vitex madiensis Oliv. and Crossopteryx febrifuga (Afzel ex G. Don)
por: Boungou-Tsona, Ghislaine, et al.
Publicado: (2023)

Effects of an Exercise and Nutritional Intervention on Circulating Biomarkers and Metabolomic Profiling During Adjuvant Treatment for Localized Breast Cancer: Results From the PASAPAS Feasibility Randomized Controlled Trial
por: Febvey-Combes, Olivia, et al.
Publicado: (2021)

Eye bank prepared versus surgeon cut endothelial graft tissue for Descemet membrane endothelial keratoplasty: An observational study
por: Regnier, Marie, et al.
Publicado: (2017)

Xanthine Oxidase Inhibitors from Filipendula ulmaria (L.) Maxim. and Their Efficient Detections by HPTLC and HPLC Analyses
por: Gainche, Maël, et al.
Publicado: (2021)

Preserving Basement Membranes during Detachment of Cultivated Oral Mucosal Epithelial Cell Sheets for the Treatment of Total Bilateral Limbal Stem Cell Deficiency
por: Rovere, Marie-Rose, et al.
Publicado: (2018)

Encapsulation of Adipose-Derived Mesenchymal Stem Cells in Calcium Alginate Maintains Clonogenicity and Enhances their Secretory Profile
por: Capin, Lucille, et al.
Publicado: (2020)

Potential Anti-Inflammatory and Chondroprotective Effect of Luzula sylvatica
por: Cholet, Juliette, et al.
Publicado: (2022)

Activation of antioxidant defences of human mammary epithelial cells under leptin depend on neoplastic state
por: Mahbouli, Sinda, et al.
Publicado: (2018)

Does aging affect the immune status? A comparative analysis in 300 healthy volunteers from France, Austria and Spain
por: Vasson, Marie-Paule, et al.
Publicado: (2013)

Transcriptome profiling reveals stress-responsive gene networks in cattle muscles
por: Cassar-Malek, Isabelle, et al.
Publicado: (2022)

Effect of Tamoxifen and Raloxifene on the Proliferative Activity of the Breast Epithelium in Premenopausal Women
por: Lucato, Miliana T, et al.
Publicado: (2015)

Effectiveness of a Global Multidisciplinary Supportive and Educational Intervention in Thermal Resort on Anthropometric and Biological Parameters, and the Disease-Free Survival after Breast Cancer Treatment Completion (PACThe)
por: Vasson, Marie-Paule, et al.
Publicado: (2020)

In Vitro Anti-Inflammatory and Immunomodulatory Activities of an Extract from the Roots of Bupleurum rotundifolium
por: Cholet, Juliette, et al.
Publicado: (2019)

25-Hydroxyvitamin D potentializes extracellular cathelicidin release from human PBMC stimulated ex vivo with either bacterial (LPS) or viral (P: IC) mimetics
por: Aldekwer, Sahar, et al.
Publicado: (2022)

Role of small proliferative adipocytes: possible beige cell progenitors
por: Taguchi, Koichiro, et al.
Publicado: (2020)

Anti-Inflammatory and Cytotoxic Potential of New Phenanthrenoids from Luzula sylvatica
por: Gainche, Maël, et al.
Publicado: (2020)

Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice
por: Rodriguez, Jonathan, et al.
Publicado: (2015)

Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase
por: Ye, Risheng, et al.
Publicado: (2015)

Characterization of a Topically Testable Model of Burn Injury on Human Skin Explants
por: Gross-Amat, Olivia, et al.
Publicado: (2020)

Smart coumarin-tagged imprinted polymers for the rapid detection of tamoxifen
por: Ray, Judith V., et al.
Publicado: (2016)

Plasma Metabolomics for Discovery of Early Metabolic Markers of Prostate Cancer Based on Ultra-High-Performance Liquid Chromatography-High Resolution Mass Spectrometry
por: Lin, Xiangping, et al.
Publicado: (2021)

Attainment of Brown Adipocyte Features in White Adipocytes of Hormone-Sensitive Lipase Null Mice
por: Ström, Kristoffer, et al.
Publicado: (2008)

Adipocyte-induced transdifferentiation of osteoblasts and its potential role in age-related bone loss
por: Clabaut, Aline, et al.
Publicado: (2021)

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation
por: Brier, Ann-Sofie B., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p6e9gdqqtsckijev4gc20925v7