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Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis

Increasing evidence indicates that microRNAs (miRNAs) are contributing factors to neurodegeneration. Alterations in miRNA signatures have been reported in several neurodegenerative dementias, but data in prion diseases are restricted to ex vivo and animal models. The present study identified signifi...

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Detalles Bibliográficos
Autores principales: Llorens, Franc, Thüne, Katrin, Martí, Eulàlia, Kanata, Eirini, Dafou, Dimitra, Díaz-Lucena, Daniela, Vivancos, Ana, Shomroni, Orr, Zafar, Saima, Schmitz, Matthias, Michel, Uwe, Fernández-Borges, Natalia, Andréoletti, Olivier, del Río, José Antonio, Díez, Juana, Fischer, Andre, Bonn, Stefan, Sklaviadis, Theodoros, Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794191/
https://www.ncbi.nlm.nih.gov/pubmed/29357384
http://dx.doi.org/10.1371/journal.ppat.1006802