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Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis
Endothelial cells respond to different levels of fluid shear stress through adaptations of their mechanosensitivity. Currently, we lack a good understanding of how this contributes to sculpting of the cardiovascular system. Cerebral cavernous malformation (CCM) is an inherited vascular disease that...
Autores principales: | Donat, Stefan, Lourenço, Marta, Paolini, Alessio, Otten, Cécile, Renz, Marc, Abdelilah-Seyfried, Salim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794256/ https://www.ncbi.nlm.nih.gov/pubmed/29364115 http://dx.doi.org/10.7554/eLife.28939 |
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