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Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses
Since the invention of systematic evolution of ligands by exponential enrichment, many short oligonucleotides (or aptamers) have been reported that can bind to a wide range of target molecules with high affinity and specificity. Previously, we reported an RNA aptamer that shows high affinity to the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794459/ https://www.ncbi.nlm.nih.gov/pubmed/29435416 http://dx.doi.org/10.1002/2211-5463.12368 |