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High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer
The gene encoding the ATPase of the chromatin remodeling SWI/SNF complexes SMARCA4 (BRG1) is often mutated or silenced in tumors, suggesting a role as tumor suppressor. Nonetheless, recent reports show requirement of SMARCA4 for tumor cells growth. Here, we performed a computational meta-analysis us...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794756/ https://www.ncbi.nlm.nih.gov/pubmed/29391527 http://dx.doi.org/10.1038/s41598-018-20217-3 |