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Contraction of T cell richness in lung cancer brain metastases

Very little is known about how the adaptive immune system responds to clonal evolution and tumor heterogeneity in non-small cell lung cancer. We profiled the T-cell receptor β complementarity determining region 3 in 20 patients with fully resected non-small cell lung cancer primary lesions and paire...

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Detalles Bibliográficos
Autores principales:	Mansfield, Aaron S., Ren, Hongzheng, Sutor, Shari, Sarangi, Vivekananda, Nair, Asha, Davila, Jaime, Elsbernd, Laura R., Udell, Julia B., Dronca, Roxana S., Park, Sean, Markovic, Svetomir N., Sun, Zhifu, Halling, Kevin C., Nevala, Wendy K., Aubry, Marie Christine, Dong, Haidong, Jen, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794798/ https://www.ncbi.nlm.nih.gov/pubmed/29391594 http://dx.doi.org/10.1038/s41598-018-20622-8

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