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Peripheral administration of lactate produces antidepressant-like effects
In addition to its role as metabolic substrate that can sustain neuronal function and viability, emerging evidence supports a role for l-lactate as an intercellular signaling molecule involved in synaptic plasticity. Clinical and basic research studies have shown that major depression and chronic st...
Autores principales: | Carrard, A, Elsayed, M, Margineanu, M, Boury-Jamot, B, Fragnière, L, Meylan, E M, Petit, J-M, Fiumelli, H, Magistretti, P J, Martin, J-L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794893/ https://www.ncbi.nlm.nih.gov/pubmed/27752076 http://dx.doi.org/10.1038/mp.2016.179 |
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