Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying bla(NDM-5) on an IncF Multidrug Resistance Plasmid and bla(OXA-181) on an IncX3 Plasmid

Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored bla(NDM-5) and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and bla(OXA-...

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Detalles Bibliográficos
Autores principales: Overballe-Petersen, Søren, Roer, Louise, Ng, Kim, Hansen, Frank, Justesen, Ulrik S., Andersen, Leif P., Stegger, Marc, Hammerum, Anette M., Hasman, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794949/
https://www.ncbi.nlm.nih.gov/pubmed/29437102
http://dx.doi.org/10.1128/genomeA.01542-17
Descripción
Sumario:Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored bla(NDM-5) and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and bla(OXA-181). E. coli isolates with both bla(NDM-5) and bla(OXA-181) carbapenemases are rare.

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