ATP12A promotes mucus dysfunction during Type 2 airway inflammation

Allergic airway disease is known to cause significant morbidity due to impaired mucociliary clearance, however the mechanism that leads to the mucus dysfunction is not entirely understood. Interleukin 13 (IL-13), a key mediator of Type 2 (T2) inflammation, profoundly alters the ion transport propert...

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Detalles Bibliográficos
Autores principales: Lennox, Alison T., Coburn, Stefanie L., Leech, John A., Heidrich, Elisa M., Kleyman, Thomas R., Wenzel, Sally E., Pilewski, Joseph M., Corcoran, Timothy E., Myerburg, Mike M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794982/
https://www.ncbi.nlm.nih.gov/pubmed/29391451
http://dx.doi.org/10.1038/s41598-018-20444-8

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