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KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

A single nucleotide polymorphism, rs17070145, in the KIdney and BRAin expressed protein (KIBRA) gene has been associated with cognition and hippocampal volume in cognitively normal (CN) individuals. However, the impact of rs17070145 on longitudinal cognitive decline and hippocampal atrophy in CN adu...

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Detalles Bibliográficos
Autores principales:	Porter, Tenielle, Burnham, Samantha C., Doré, Vincent, Savage, Greg, Bourgeat, Pierrick, Begemann, Kimberly, Milicic, Lidija, Ames, David, Bush, Ashley I., Maruff, Paul, Masters, Colin L., Rowe, Christopher C., Rainey-Smith, Stephanie, Martins, Ralph N., Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Laws, Simon M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794989/ https://www.ncbi.nlm.nih.gov/pubmed/29391469 http://dx.doi.org/10.1038/s41598-018-20513-y

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