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Large-scale intact glycopeptide identification by Mascot database search

Workflows capable of determining glycopeptides in large-scale are missing in the field of glycoproteomics. We present an approach for automated annotation of intact glycopeptide mass spectra. The steps in adopting the Mascot search engine for intact glycopeptide analysis included: (i) assigning one...

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Detalles Bibliográficos
Autores principales: Bollineni, Ravi Chand, Koehler, Christian Jeffrey, Gislefoss, Randi Elin, Anonsen, Jan Haug, Thiede, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795011/
https://www.ncbi.nlm.nih.gov/pubmed/29391424
http://dx.doi.org/10.1038/s41598-018-20331-2