Cargando…

Resistance to HIV Integrase Inhibitors: About R263K and E157Q Mutations

The use of integrase inhibitors (INI) is increasing in antiretroviral therapies (ART) and INI are not all equal regarding genetic barrier to resistance. The aim of this manuscript was to review main in vivo and in vitro knowledge about two particular integrase resistance-associated mutations: R263K...

Descripción completa

Detalles Bibliográficos
Autores principales: Charpentier, Charlotte, Descamps, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795454/
https://www.ncbi.nlm.nih.gov/pubmed/29346270
http://dx.doi.org/10.3390/v10010041