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Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore
We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia de...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795457/ https://www.ncbi.nlm.nih.gov/pubmed/29346272 http://dx.doi.org/10.3390/v10010044 |
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author | Tan, Cheong Huat Tan, Li Kiang Hapuarachchi, Hapuarachchige Chanditha Lai, Yee Ling Wong, Pei Sze Jeslyn Yap, Grace Mak, Keng Wai Wong, Wing Yan Leo, Yee Sin Wong, Mei Chun Ng, Lee Ching |
author_facet | Tan, Cheong Huat Tan, Li Kiang Hapuarachchi, Hapuarachchige Chanditha Lai, Yee Ling Wong, Pei Sze Jeslyn Yap, Grace Mak, Keng Wai Wong, Wing Yan Leo, Yee Sin Wong, Mei Chun Ng, Lee Ching |
author_sort | Tan, Cheong Huat |
collection | PubMed |
description | We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions. |
format | Online Article Text |
id | pubmed-5795457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-57954572018-02-09 Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore Tan, Cheong Huat Tan, Li Kiang Hapuarachchi, Hapuarachchige Chanditha Lai, Yee Ling Wong, Pei Sze Jeslyn Yap, Grace Mak, Keng Wai Wong, Wing Yan Leo, Yee Sin Wong, Mei Chun Ng, Lee Ching Viruses Case Report We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions. MDPI 2018-01-18 /pmc/articles/PMC5795457/ /pubmed/29346272 http://dx.doi.org/10.3390/v10010044 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Tan, Cheong Huat Tan, Li Kiang Hapuarachchi, Hapuarachchige Chanditha Lai, Yee Ling Wong, Pei Sze Jeslyn Yap, Grace Mak, Keng Wai Wong, Wing Yan Leo, Yee Sin Wong, Mei Chun Ng, Lee Ching Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title | Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title_full | Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title_fullStr | Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title_full_unstemmed | Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title_short | Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore |
title_sort | viral and antibody kinetics, and mosquito infectivity of an imported case of zika fever due to asian genotype (american strain) in singapore |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795457/ https://www.ncbi.nlm.nih.gov/pubmed/29346272 http://dx.doi.org/10.3390/v10010044 |
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