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U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection

In this work we show an optical fiber evanescent wave absorption probe for glucose detection in different physiological media. High selectivity is achieved by functionalizing the surface of an only-core poly(methyl methacrylate) (PMMA) polymer optical fiber with phenilboronic groups, and enhanced se...

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Autores principales: Azkune, Mikel, Ruiz-Rubio, Leire, Aldabaldetreku, Gotzon, Arrospide, Eneko, Pérez-Álvarez, Leyre, Bikandi, Iñaki, Zubia, Joseba, Vilas-Vilela, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795775/
https://www.ncbi.nlm.nih.gov/pubmed/29295579
http://dx.doi.org/10.3390/s18010034
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author Azkune, Mikel
Ruiz-Rubio, Leire
Aldabaldetreku, Gotzon
Arrospide, Eneko
Pérez-Álvarez, Leyre
Bikandi, Iñaki
Zubia, Joseba
Vilas-Vilela, Jose Luis
author_facet Azkune, Mikel
Ruiz-Rubio, Leire
Aldabaldetreku, Gotzon
Arrospide, Eneko
Pérez-Álvarez, Leyre
Bikandi, Iñaki
Zubia, Joseba
Vilas-Vilela, Jose Luis
author_sort Azkune, Mikel
collection PubMed
description In this work we show an optical fiber evanescent wave absorption probe for glucose detection in different physiological media. High selectivity is achieved by functionalizing the surface of an only-core poly(methyl methacrylate) (PMMA) polymer optical fiber with phenilboronic groups, and enhanced sensitivity by using a U-shaped geometry. Employing a supercontinuum light source and a high-resolution spectrometer, absorption measurements are performed in the broadband visible light spectrum. Experimental results suggest the feasibility of such a fiber probe as a low-cost and selective glucose detector.
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spelling pubmed-57957752018-02-13 U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection Azkune, Mikel Ruiz-Rubio, Leire Aldabaldetreku, Gotzon Arrospide, Eneko Pérez-Álvarez, Leyre Bikandi, Iñaki Zubia, Joseba Vilas-Vilela, Jose Luis Sensors (Basel) Article In this work we show an optical fiber evanescent wave absorption probe for glucose detection in different physiological media. High selectivity is achieved by functionalizing the surface of an only-core poly(methyl methacrylate) (PMMA) polymer optical fiber with phenilboronic groups, and enhanced sensitivity by using a U-shaped geometry. Employing a supercontinuum light source and a high-resolution spectrometer, absorption measurements are performed in the broadband visible light spectrum. Experimental results suggest the feasibility of such a fiber probe as a low-cost and selective glucose detector. MDPI 2017-12-25 /pmc/articles/PMC5795775/ /pubmed/29295579 http://dx.doi.org/10.3390/s18010034 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Azkune, Mikel
Ruiz-Rubio, Leire
Aldabaldetreku, Gotzon
Arrospide, Eneko
Pérez-Álvarez, Leyre
Bikandi, Iñaki
Zubia, Joseba
Vilas-Vilela, Jose Luis
U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title_full U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title_fullStr U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title_full_unstemmed U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title_short U-Shaped and Surface Functionalized Polymer Optical Fiber Probe for Glucose Detection
title_sort u-shaped and surface functionalized polymer optical fiber probe for glucose detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795775/
https://www.ncbi.nlm.nih.gov/pubmed/29295579
http://dx.doi.org/10.3390/s18010034
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