Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

PURPOSE: Sex hormones may be associated with primary open-angle glaucoma (POAG), although the mechanisms are unclear. We previously observed that gene variants involved with estrogen metabolism were collectively associated with POAG in women but not men; here we assessed gene variants related to tes...

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Autores principales: Cooke Bailey, Jessica N., Gharahkhani, Puya, Kang, Jae H., Butkiewicz, Mariusz, Sullivan, David A., Weinreb, Robert N., Aschard, Hugues, Allingham, R. Rand, Ashley-Koch, Allison, Lee, Richard K., Moroi, Sayoko E., Brilliant, Murray H., Wollstein, Gadi, Schuman, Joel S., Fingert, John H., Budenz, Donald L., Realini, Tony, Gaasterland, Terry, Scott, William K., Singh, Kuldev, Sit, Arthur J., Igo, Robert P., Song, Yeunjoo E., Hark, Lisa, Ritch, Robert, Rhee, Douglas J., Vollrath, Douglas, Zack, Donald J., Medeiros, Felipe, Vajaranant, Thasarat S., Chasman, Daniel I., Christen, William G., Pericak-Vance, Margaret A., Liu, Yutao, Kraft, Peter, Richards, Julia E., Rosner, Bernard A., Hauser, Michael A., Craig, Jamie E., Burdon, Kathryn P., Hewitt, Alex W., Mackey, David A., Haines, Jonathan L., MacGregor, Stuart, Wiggs, Janey L., Pasquale, Louis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795896/
https://www.ncbi.nlm.nih.gov/pubmed/29392307
http://dx.doi.org/10.1167/iovs.17-22708

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