Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration

PURPOSE: A large body of evidence supports a central role for complement activation in the pathobiology of age-related macular degeneration (AMD), including plasma complement component 5a (C5a). Interestingly, C5a is a chemotactic agent for monocytes, a cell type also shown to contribute to AMD. How...

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Detalles Bibliográficos
Autores principales: Toomey, Christopher B., Landowski, Michael, Klingeborn, Mikael, Kelly, Una, Deans, John, Dong, Holly, Harrabi, Ons, Van Blarcom, Thomas, Yeung, Yik Andy, Grishanin, Ruslan, Lin, John C., Saban, Daniel R., Bowes Rickman, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795897/
https://www.ncbi.nlm.nih.gov/pubmed/29392311
http://dx.doi.org/10.1167/iovs.17-23134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795897/
https://www.ncbi.nlm.nih.gov/pubmed/29392311
http://dx.doi.org/10.1167/iovs.17-23134

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