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A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies

PURPOSE: Our goal was to generate and characterize a new mouse model in which only angiogenesis- and glaucoma-relevant tissues would be naturally fluorescent. The Matrix Gla (MGP) gene is highly expressed in vascular smooth muscle cells (VSMC) and trabecular meshwork (TM). We sought to direct our Mg...

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Detalles Bibliográficos
Autores principales: Asokan, Priyadarsini, Mitra, Rajendra N., Periasamy, Ramesh, Han, Zongchao, Borrás, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795899/
https://www.ncbi.nlm.nih.gov/pubmed/29392320
http://dx.doi.org/10.1167/iovs.17-22992