Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Aurora kinases (AKs) are serine/threonine kinases that are essential for cell division. Humans have three AK genes: AKA, AKB, and AKC. AKA is required for centrosome assembly, centrosome separation, and bipolar spindle assembly, and its mutation leads to abnormal spindle morphology. AKB is required...

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Detalles Bibliográficos
Autores principales: Seeling, Joni M., Farmer, Alexis A., Mansfield, Adam, Cho, Hyuk, Choudhary, Madhusudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796022/
https://www.ncbi.nlm.nih.gov/pubmed/29283376
http://dx.doi.org/10.3390/ijms19010072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796022/
https://www.ncbi.nlm.nih.gov/pubmed/29283376
http://dx.doi.org/10.3390/ijms19010072

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