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Motor, Somatosensory, Viscerosensory and Metabolic Impairments in a Heterozygous Female Rat Model of Rett Syndrome

Rett Syndrome (RTT), an autism-related disorder caused by mutation of the X-linked Methyl CpG-binding Protein 2 (MECP2) gene, is characterized by severe cognitive and intellectual deficits. While cognitive deficits are well-documented in humans and rodent models, impairments of sensory, motor and me...

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Detalles Bibliográficos
Autores principales: Bhattacherjee, Aritra, Winter, Michelle K., Eggimann, Linda S., Mu, Ying, Gunewardena, Sumedha, Liao, Zhaohui, Christianson, Julie A., Smith, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796047/
https://www.ncbi.nlm.nih.gov/pubmed/29286317
http://dx.doi.org/10.3390/ijms19010097