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Rosiglitazone as a Modulator of TLR4 and TLR3 Signaling Pathways in Rat Primary Neurons and Astrocytes

An antidiabetic drug of the thiazolidinedione class, rosiglitazone (RG) demonstrates anti-inflammatory properties in various brain pathologies. The mechanism of RG action in brain cells is not fully known. To unravel mechanisms of RG modulation of toll-like receptor (TLR) signaling pathways, we comp...

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Detalles Bibliográficos
Autores principales: Chistyakov, Dmitry V., Azbukina, Nadezda V., Lopachev, Alexandr V., Kulichenkova, Ksenia N., Astakhova, Alina A., Sergeeva, Marina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796062/
https://www.ncbi.nlm.nih.gov/pubmed/29301276
http://dx.doi.org/10.3390/ijms19010113

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