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Rosiglitazone as a Modulator of TLR4 and TLR3 Signaling Pathways in Rat Primary Neurons and Astrocytes
An antidiabetic drug of the thiazolidinedione class, rosiglitazone (RG) demonstrates anti-inflammatory properties in various brain pathologies. The mechanism of RG action in brain cells is not fully known. To unravel mechanisms of RG modulation of toll-like receptor (TLR) signaling pathways, we comp...
Autores principales: | Chistyakov, Dmitry V., Azbukina, Nadezda V., Lopachev, Alexandr V., Kulichenkova, Ksenia N., Astakhova, Alina A., Sergeeva, Marina G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796062/ https://www.ncbi.nlm.nih.gov/pubmed/29301276 http://dx.doi.org/10.3390/ijms19010113 |
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