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Salvia Species as Sources of Natural Products with Antiprotozoal Activity
Natural products from plants have been used since ancestral times to treat a wide variety of diseases worldwide. Plants of the genus Salvia (Sage) have been reported to be used for the prevention and treatment of various diseases and ailments. In particular, some Salvia species have been used in tra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796210/ https://www.ncbi.nlm.nih.gov/pubmed/29337909 http://dx.doi.org/10.3390/ijms19010264 |
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author | Llurba-Montesino, Núria Schmidt, Thomas J. |
author_facet | Llurba-Montesino, Núria Schmidt, Thomas J. |
author_sort | Llurba-Montesino, Núria |
collection | PubMed |
description | Natural products from plants have been used since ancestral times to treat a wide variety of diseases worldwide. Plants of the genus Salvia (Sage) have been reported to be used for the prevention and treatment of various diseases and ailments. In particular, some Salvia species have been used in traditional medicine to treat diseases caused by protozoan parasites of the genera Trypanosoma, Leishmania and Plasmodium and scientific studies have demonstrated the activity of various isolated constituents from these plants against these pathogens. The current review attempts to give a critical overview of published information about the antiprotozoal activity of species of the genus Salvia and their chemical constituents. It is meant to give a unified overview of these results in order to avoid repetitions caused, e.g., by limited access to some primary reports, and to stimulate further research to possibly facilitate the development of new molecular leads against protozoal neglected tropical diseases (NTDs) based on Salvia constituents. |
format | Online Article Text |
id | pubmed-5796210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-57962102018-02-09 Salvia Species as Sources of Natural Products with Antiprotozoal Activity Llurba-Montesino, Núria Schmidt, Thomas J. Int J Mol Sci Review Natural products from plants have been used since ancestral times to treat a wide variety of diseases worldwide. Plants of the genus Salvia (Sage) have been reported to be used for the prevention and treatment of various diseases and ailments. In particular, some Salvia species have been used in traditional medicine to treat diseases caused by protozoan parasites of the genera Trypanosoma, Leishmania and Plasmodium and scientific studies have demonstrated the activity of various isolated constituents from these plants against these pathogens. The current review attempts to give a critical overview of published information about the antiprotozoal activity of species of the genus Salvia and their chemical constituents. It is meant to give a unified overview of these results in order to avoid repetitions caused, e.g., by limited access to some primary reports, and to stimulate further research to possibly facilitate the development of new molecular leads against protozoal neglected tropical diseases (NTDs) based on Salvia constituents. MDPI 2018-01-16 /pmc/articles/PMC5796210/ /pubmed/29337909 http://dx.doi.org/10.3390/ijms19010264 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Llurba-Montesino, Núria Schmidt, Thomas J. Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title | Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title_full | Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title_fullStr | Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title_full_unstemmed | Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title_short | Salvia Species as Sources of Natural Products with Antiprotozoal Activity |
title_sort | salvia species as sources of natural products with antiprotozoal activity |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796210/ https://www.ncbi.nlm.nih.gov/pubmed/29337909 http://dx.doi.org/10.3390/ijms19010264 |
work_keys_str_mv | AT llurbamontesinonuria salviaspeciesassourcesofnaturalproductswithantiprotozoalactivity AT schmidtthomasj salviaspeciesassourcesofnaturalproductswithantiprotozoalactivity |