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Adrenergic Agonists Bind to Adrenergic-Receptor-Like Regions of the Mu Opioid Receptor, Enhancing Morphine and Methionine-Enkephalin Binding: A New Approach to “Biased Opioids”?

Extensive evidence demonstrates functional interactions between the adrenergic and opioid systems in a diversity of tissues and organs. While some effects are due to receptor and second messenger cross-talk, recent research has revealed an extracellular, allosteric opioid binding site on adrenergic...

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Detalles Bibliográficos
Autores principales:	Root-Bernstein, Robert, Turke, Miah, Subhramanyam, Udaya K. Tiruttani, Churchill, Beth, Labahn, Joerg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796218/ https://www.ncbi.nlm.nih.gov/pubmed/29342106 http://dx.doi.org/10.3390/ijms19010272

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